The effects of magic mushrooms differ from person to person. Therefore, the onset and duration of the effects also have a wide range of variation. Users can control their dosage intake by knowing how psilocybin, the primary ingredient in hallucinogenic mushrooms, behaves in the body and what variables affect how long its effects last.
Psilocybin users should use the right dosage, as with all substances, in order to have a positive experience. The last thing anyone wants while using psychedelics is a negative experience.
This article will discuss psilocybin, how it works, and factors that can affect the duration of its effects.
What are Shrooms?
Shrooms are a particular kind of mushroom that contains the hallucinogenic substance psilocybin. They are often referred to as magic mushrooms, psilocybin mushrooms, or simply shrooms.
Psilocybin has been used for generations to cause hallucinogenic effects, increase consciousness and perception, and elicit euphoric feelings. The usage is widespread among both recreational and medical users.
What is Psilocybin and How It Works
We cannot discuss the effects and anything related to shrooms without discussing psilocybin.
The naturally occurring substance psilocybin, which is present in over 200 kinds of mushrooms, may one day change how we treat depression. This compound is structurally identical to serotonin, which controls mood and perception.
Psilocybin is a prodrug which remains inactive until it is consumed and processed by the body. When in the body, it is metabolized to the active compound “psilocin,” which predominantly serves as a partial agonist for the 5-HT2A receptor.
The metabolite psilocin functions as a partial agonist to a lesser extent on 5-HT1A, 5-HT1D, and 5-HT2D receptors, in the basal ganglia, leading to increased dopamine. The complicated mechanism of the compound is said to cause the effects that users experience.
Serotonin receptors are typically activated by psilocin in the prefrontal cortex. This area influences perception and mood. Additionally, it affects the parts of the brain that control arousal and panic reactions.
It’s not a given that psilocin usually produces vivid or audible hallucinations. Instead, psilocybin alters how certain users see things and people already in their environment.
When Do Effects Start to Kick In?
Psilocybin takes some time to start affecting the body after consumption. According to research, hallucinatory effects can manifest in 20–40 minutes. Most people claim to experience the effects within an hour, while there are occasional exceptions.
These outcomes could develop gradually. A person may initially have mild sensory or emotional alterations, followed by increased visual, auditory, or other sensory hallucinations.
How Long Do They Last?
On average, a trip lasts between 3 and 6 hours, but some people may feel the effects for much longer. You’re likely to have some after-effects from your trip that could continue into the next day. This is due to elements that can impact how strong and long-lasting the effect can remain. Most people resume feeling like themselves within a day.
Factors Affecting Shrooms Effects on the Body
It is believed that whenever a user consumes Psilocybe on an empty stomach, it will be absorbed more quickly than those who take them with food (or after a meal). It is possible to hypothesize that eating while taking mushrooms will alter excretion times. Additionally, the degree of hydration may affect systemic clearance because the primary method through which the active compounds are removed is through urine.
Strain Potency and Dosage
The amount or dosage a person consumes will affect how long the trip will last. The longer it takes to eliminate a substance, the higher the dose a person takes (particularly concerning their body size).
Additionally, some species are known to be more potent than others, which means they contain a higher amount of psilocybin. It will take longer for the active ingredient to stay in the body if users consume a powerful strain.
Mode of Intake
How you consume mushrooms can affect how long psilocybin and its metabolites linger in your system. The dried versions are typically consumed orally by being eaten “as is” or brewed into tea.
Eating them “as is” gives a potent and fast experience compared to edibles. The latter can be potent, but it takes time for the effects to kick in. Therefore, it lasts longer. Lemon Tek is another method that can speed up the onset and duration of psilocybin.
How long the effects endure depends on age, general health, and metabolic rate. In general, your trip will be shorter, and psilocybin will leave your body faster if you are younger and have a faster metabolism.
The exact explanation for how long do shrooms last in the body or their onset is unclear. There are multiple factors influencing the effects, onset, and experience. The length of a trip can vary depending on the shroom strain, metabolism, dose, and mode of intake, as was already mentioned. The essential thing to consider is always starting at a low dosage and gradually increasing the amount after a few hours to prevent experiencing overwhelming psychedelic trips.
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